Abstract
Mpox remains a major public health concern in Central Africa, particularly in the Democratic Republic of Congo, where persistent community transmission has been documented for decades (WHO, 2023). The recurrent outbreaks in urban settings such as Kinshasa highlight the need for updated evidence on household knowledge, attitudes and practices (KAP) to strengthen prevention strategies. This study assesses KAP related to mpox among households residing in Masina 2 Health Zone and identifies key determinants of preventive behavior. A population-based cross-sectional survey was conducted among randomly selected households. A structured questionnaire, adapted from WHO rapid epidemic assessment tools (WHO, 2022), was administered to household heads. Data were collected on knowledge (transmission, symptoms, treatment), attitudes (risk perception, stigma) and practices (hygiene measures, care-seeking, isolation). Statistical analyses described overall patterns and explored associated predictors. Preliminary findings reveal significant gaps in understanding human-to-human transmission and recognition of early clinical symptoms. The study underscores the crucial role of health education, reliable information sources, and community engagement in improving preventive behavior. These findings will support the adaptation of community-based mpox response and communication strategies within densely populated urban areas such as Masina 2.
References
1. Bunge, E. M., Hoet, B., Chen, L., et al. (2022). The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLOS Neglected Tropical Diseases, 16(2), e0010141.
2. Centers for Disease Control and Prevention. (2023). Mpox outbreak global update. CDC.
3. Creswell, J. W. (2014). Research design: Qualitative, quantitative, and mixed methods approaches (4th ed.). SAGE.
4. Hosmer, D. W., & Lemeshow, S. (2000). Applied logistic regression (2nd ed.). Wiley.
5. Lemeshow, S., Hosmer, D. W., Klar, J., & Lwanga, S. K. (1990). Adequacy of sample size in health studies. World Health Organization.
6. Morgan, R., Baker, P., Ochola, E., Klaasen, B., & Salami, B. (2022). Mpox and public health communication: Addressing stigma and improving community responses. The Lancet Infectious Diseases, 22(11), 1512–1514.
7. Organisation mondiale de la Santé (OMS). (2022). Outils d’évaluation CAP en situation d’épidémie.
8. Organisation mondiale de la Santé (OMS). (2022). Outils d’évaluation rapide en situations d’épidémie : Modules CAP pour les maladies à potentiel épidémique.
9. Organisation mondiale de la Santé. (2023). Mpox situation update: Global epidemiological overview. OMS.
10. Rimoin, A. W., Mulembakani, P. M., Johnston, S. C., et al. (2010). Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo. PNAS, 107(37), 16262–16267.
11. J. O., Kisalu, N. K., Kinkela, T. L., … & Meyer, H. (2010). Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo. PNAS, 107(37), 16262–16267. https://doi.org/10.1073/pnas.1005769107
12. Tindana, P., Kass, N., & Akweongo, P. (2007). The informed consent process in a rural African setting: A case study of the Kassena-Nankana district of northern Ghana. IRB: Ethics & Human Research, 29(3), 1–6.

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Copyright (c) 2026 Ekeni et al.
